Yoel Drubin was born in Gertingen, in the Kovna district. He received a religious education and went to Germany to continue his education. As a member of the "Bilu" group he immigrated to Eretz Israel in July 1882. Together with his friends from the group, he lived in the home of Anton Iyov, worked in the Mikveh Israel Agricultural School and was among the members who wrote the "Bilu" Regulations in October 1882. Several months later he settled in Rishon Le-Zion and was a winegrower and farmer.
He was active in public affairs: a member of the Village Committee (1890, 1894, 1895-6, 1900, 1904, 1905-6, 1921); member of the Agricultural Committee (1919-20); member of the Rishon Le-Zion and Zichron Yaakov Winery Council and a member of the Control Board of the Winegrowers' Association; delegate sent to Paris (1906) to draw the contract of the I.C.A (Jewish Colonization Association); member of the Winegrowers' delegation to Paris (1911) to renew contact with the Baron Rothschild and the I.C.A.; sent to Vienna (1907) to carry out the liquidation of the Carmel Mizrachi branch there; member of "Kupah Haklait" (Farmers' Fund) in Rishon Le-Zion and a member of its administration (1923).